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Attacking Neurodegenerative Diseases with Protein Degraders
The use of protein degraders is a promising area of emerging small molecule therapies. Rather than inhibit disease-causing proteins, degraders use a natural cellular process to break them down. Origami Therapeutics is using its proprietary drug discovery platform to...
Origami Brings Protein Degradation to Neurodegenerative Disorders
Protein degradation is an up-and-coming approach that most often is used in oncology. Now, Origami Therapeutics is among the first to apply it to genetic neurodegenerative disorders, targeting proteins that otherwise have been considered undruggable. Read full article
Founder Spotlight #36: Beth Hoffman @ Origami Therapeutics
Beth Hoffman is Founder, President, & CEO @ Origami Therapeutics. She brings more than 25 years experience of CNS drug discovery and has developed over 30 assets that have advanced into the clinic in cystic fibrosis, metabolic diseases, neurology, pain, and...
CEO Beth Hoffman guest on the Personalized Medicine Podcast
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Origami named part of the W22 Batch at Y Combinator
Oral drugs to halt neurodegeneration Origami Therapeutics, Inc. is a biotech company developing novel protein degraders with potential to delay or halt disease progression by eliminating toxic proteins from the body. Our drug discovery platform leverages our...
Other events happening for Origami
28 Feb – 3 March, 2022 Presenting at 17th Annual Huntington’s Disease Therapeutics Conference https://web.cvent.com/event/a0991146-7ae2-4f10-bc6c-0bf856caac34/summary 28-30 March, 2022 Presenting at 10th Annual Neurodegenerative Drug Development Summit...
Panel Chair and Presenting at TPD Emerging Disease Applications Beyond Oncology
Targeted protein degradation (TPD) is emerging to be a promising technology for targeting disease-causing proteins. Through the mechanism of hijacking either the ubiquitin-proteasome system (UPS) or the autophagy-lysosomal pathway the protein of interest is degraded,...
Listed as one of BioCentury’s 2021 Class of Emerging Companies
Learn more about Origami, one of Biocenturys 2021 class of emerging companies.
Panelist at BioTech Showcase 2022- Rare Disease: The Value Proposition Keeps Expanding
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CEO Beth Hoffman named to HDSA National Board of Trustees
The Huntington’s Disease Society of America (HDSA) is proud to announce that Jeff Carroll, PhD and Beth Hoffman, PhD have been elected to the Society’s National Board of Trustees. Learn More
Panelist at RESI Digital: Investing in Precision Medicine
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MedCity News Article
Origami Therapeutics developing treatments for neurodegenerative diseases with ML and computational chemistry. Learn more
WIB-National Second Annual Founders Showcase (presenting company)
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BioCentury Article
Emerging Company Profile – Origami: Correcting or eliminating misfolded proteins. Learn More
Demy Colton BioFuture Conference
Presenting Company event information
Panelist at Finance and Accounting for Bioscience Companies (CFO Leslie Shulze)
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CNS Therapeutics Xchange
Presentation: Triaging Your Drug Targets to Find the Most Relevant Lead (CEO Beth Hoffman) https://www.hub-xchange.com/cns-therapeutics-xchange-west-coast-2021/#anchor1
Origami CEO, Beth Hoffman, appointed to RCF SAB
The Tau Consortium is a collaborative research program that is managed and funded by the Rainwater Charitable Foundation in partnership with other funders. Read More
Origami Therapeutics Selected as a CONNECT Cool Company of 2021
SAN DIEGO, May 4, 2021 /PRNewswire/ -- Origami Therapeutics http://origamitherapeutics.com,a discovery-stage company taking a precision medicine approach to discover diseasemodifyingtreatments for neurodegeneration, announced today it has been selected as one of13...
LABEST 2021 Pitch Competition Finalist
LABEST 2021 Full Agenda 5.17