San Diego based Origami Therapeutics is developing next-generation protein degraders and correctors for CNS conditions – the lead program is focused on Huntington’s disease

Jun 27, 2026

Founder & CEO Beth Hoffman describes how Origami’s platform is different than other degrades like PROTACs, and how it specifically is designed to clear the mutant huntingtin protein. Plus, details on a global collaboration announced earlier this year with Ipsen.

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