Developing next-generation disease-modifying protein degraders and correctors

Developing next-generation disease-modifying protein degraders and correctors

Neurodegenerative Diseases

At Origami Therapeutics, we’re leading the creation of an entirely new way to treat disease through therapies that target and degrade disease-related proteins… learn more

How We’re Different

Protein Degradation

To selectively and efficiently degrade and remove disease-causing proteins while sparing normal forms of the protein.

Small Molecules

For broad distribution in the body and ease of manufacture.

Neurodegenerative Diseases

Alzheimer’s, Huntington’s, and Parkinson’s Diseases, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia